Use of Laccase Enzymes as Bio-Receptors for the Organic Dye Methylene Blue in a Surface Plasmon Resonance Biosensor
2024

Using Laccase Enzymes to Detect Methylene Blue in Water

publication 10 minutes Evidence: moderate

Author Information

Author(s): Sánchez-Álvarez Araceli, Quintanilla-Villanueva Gabriela Elizabeth, Rodríguez-Quiroz Osvaldo, Rodríguez-Delgado Melissa Marlene, Villarreal-Chiu Juan Francisco, Sicardi-Segade Analía, Luna-Moreno Donato

Primary Institution: Electromecánica Industrial, Universidad Tecnológica de León

Hypothesis

Can laccase enzymes be effectively used as bio-receptors for detecting methylene blue in a biosensor?

Conclusion

The study successfully developed a biosensor that detects methylene blue with a limit of detection of 4.61 mg L−1 and a recovery rate of 122.46 ± 4.41% from spiked rainwater samples.

Supporting Evidence

  • The biosensor maintained a stable signal over 17 cycles and was effective for 30 days at room temperature.
  • The method demonstrated a limit of detection of 4.61 mg L−1 and a limit of quantification of 15.37 mg L−1.
  • A spiked rainwater sample yielded a recovery rate of 122.46 ± 4.41%.

Takeaway

Scientists created a special sensor that uses enzymes to find a harmful dye in water, showing it works well and can be reused.

Methodology

The study involved developing a Surface Plasmon Resonance biosensor using laccases immobilized on a gold surface to detect methylene blue.

Limitations

The limit of detection is higher than some conventional methods, and the study suggests that further optimization could improve sensitivity.

Statistical Information

P-Value

4.61 mg L−1

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.3390/s24248008

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