Chronic Traffic-Related Air Pollution and Stress Interact to Predict Biologic and Clinical Outcomes in Asthma
2008

Traffic Pollution and Family Stress Affect Asthma in Children

Sample size: 73 publication 10 minutes Evidence: moderate

Author Information

Author(s): Edith Chen, Hannah M. C. Schreier, Robert C. Strunk, Michael Brauer

Primary Institution: University of British Columbia

Hypothesis

This study aimed to test interactions between chronic exposure to traffic-related air pollution and chronic family stress in predicting biologic and clinical outcomes in children with asthma.

Conclusion

The study found that interactions between traffic-related air pollution and family stress significantly predicted both biological and clinical outcomes in children with asthma.

Supporting Evidence

  • Higher chronic stress was associated with increased inflammatory markers as pollution levels decreased.
  • Children in high pollution areas had more asthma symptoms than those in low pollution areas.
  • Chronic stress exacerbated asthma symptoms over time in lower pollution areas.

Takeaway

Kids with asthma can get worse when there's a lot of traffic pollution, especially if they're also dealing with family stress.

Methodology

Children with asthma were interviewed about life stress, and inflammatory markers were measured, with pollution exposure assessed using a land use regression model for nitrogen dioxide concentrations.

Potential Biases

Potential misclassification of pollution exposure if families moved during the study period.

Limitations

The study had a small sample size and varying time frames for measures, which may affect the findings.

Participant Demographics

Children aged 9–18 years, 68% male, 63% white.

Statistical Information

P-Value

p = 0.02

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1289/ehp.11076

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