Rheumatic Manifestations of Sarcoidosis
Author Information
Author(s): Day Julia, Hamann Philip D. H.
Primary Institution: North Bristol NHS Foundation Trust, Bristol, UK; Musculoskeletal Research Unit, University of Bristol, UK
Conclusion
Sarcoidosis can present with various musculoskeletal manifestations, including acute and chronic arthritis, bone disease, and myopathy, with treatment primarily involving glucocorticoids.
Supporting Evidence
- Musculoskeletal manifestations are reported in 10–40% of patients with sarcoidosis.
- Diagnosis is confirmed through histological evidence of non-caseating granuloma on tissue biopsy.
- Acute sarcoid arthritis has a very good prognosis and is usually self-limiting.
- Chronic arthritis and muscle involvement often occur in the context of more widespread systemic disease.
- Glucocorticoids are the mainstay of treatment for joint and muscle disease in sarcoidosis.
Takeaway
Sarcoidosis is a disease that can affect many parts of the body, especially the joints and muscles, and doctors usually treat it with steroids.
Methodology
This review article provides an overview of the musculoskeletal manifestations of sarcoidosis and discusses diagnostic challenges and treatment options.
Limitations
The review is based on existing literature and may not cover all recent findings or clinical practices.
Participant Demographics
Sarcoidosis can affect individuals of all ages and ethnicities, with higher incidence noted in African American and Scandinavian populations.
Digital Object Identifier (DOI)
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