Valvular involvement in ANCA-associated systemic vasculitis: a case report and literature review
2011

Valvular Involvement in ANCA-Associated Systemic Vasculitis: A Case Report

Sample size: 1 publication Evidence: low

Author Information

Author(s): Lacoste Chloé, Mansencal Nicolas, Benmrad Mona, Goulon-Goeau Catherine, Cohen Pascal, Guillevin Loïc, Hanslik Thomas

Primary Institution: Assistance Publique Hôpitaux de Paris (AP-HP)

Hypothesis

What is the nature and management of cardiac valvular involvement in ANCA-associated systemic vasculitis?

Conclusion

Valvular involvement in ANCA-associated systemic vasculitides is rare and often requires valve replacement.

Supporting Evidence

  • Cardiac valvular involvement is rarely diagnosed in ANCA-associated systemic vasculitides.
  • Most valvular lesions are due to Wegener's granulomatosis.
  • Aortic regurgitation is the most frequent type of valvular lesion.
  • Half of the valvular lesions are present at the time of vasculitis diagnosis.
  • Valve replacement is often required in cases of valvular involvement.

Takeaway

This study talks about a man who had a heart valve problem because of a rare disease, and he needed surgery to fix it.

Methodology

Case report and literature review.

Limitations

The study is based on a single case report and a review of existing literature.

Participant Demographics

A 44-year-old male from Bangladesh.

Digital Object Identifier (DOI)

10.1186/1471-2474-12-50

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