Efficacy of Hongjing I Granule for Erectile Dysfunction
Author Information
Author(s): Xu Run-Nan, Guo Jun, Zhang Chun-He, Zhou Qing, Gen Qiang, Wang Fu, Zhao Yu, Luo Xin-Yun, Li Yan-Feng, Fu Yi-Jia, Zhang Xin, Wang Wen-Zhi, Ma Jian-Xiong, Wang Jian, Huang Xiao-Jun, Huang Wen-Jie, Lv Bo-Dong
Primary Institution: The Second Affiliated Hospital, Zhejiang University, Hangzhou, Zhejiang, China
Hypothesis
The Hongjing I granule (HJIG) is more effective than a placebo in improving erectile function in patients with mild to moderate erectile dysfunction.
Conclusion
The Hongjing I granule significantly improved symptoms in patients with mild to moderate erectile dysfunction.
Supporting Evidence
- The HJIG group showed a mean change in IIEF-EF scores of 7.80 compared to 3.33 in the placebo group.
- Improvements in TCM symptom scores were greater in the HJIG group than in the placebo group.
- No adverse events were reported across both groups.
- Statistically significant differences were observed in primary outcomes between the HJIG and placebo groups.
- Participants adhered to at least 80% of the prescribed dosage.
Takeaway
This study tested a herbal medicine called Hongjing I granule to see if it helps men with trouble getting erections. It found that the herbal medicine worked better than a fake treatment.
Methodology
A multicenter, double-blind, randomized, placebo-controlled trial with 122 patients over 8 weeks.
Potential Biases
Participants more inclined towards herbal treatment may have skewed results.
Limitations
The study had a relatively small sample size and potential biases due to self-selection.
Participant Demographics
Men aged 22 to 65 with mild to moderate erectile dysfunction.
Statistical Information
P-Value
p<0.001
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
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