New aspects of thyroid hormone synthesis and action
2011
New Aspects of Thyroid Hormone Synthesis and Action
publication
Author Information
Author(s): Heike Biebermann
Primary Institution: Charité Universitätsmedizin Berlin
Hypothesis
What defines thyroid health?
Conclusion
Recent findings highlight the importance of understanding thyroid hormone synthesis and action for improving diagnosis and therapy of thyroid disorders.
Supporting Evidence
- A novel germline TSH-receptor mutation was linked to non-autoimmune hyperthyroidism.
- Mutations in MCT8 are associated with Allan-Herndon Dudley syndrome.
- Non-classical actions of thyroid hormones activate alternative signaling pathways.
Takeaway
Scientists are learning more about how thyroid hormones work and how to better treat thyroid problems.
Digital Object Identifier (DOI)
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