Case report: Pheochromocytoma-induced pseudo-Cushing’s syndrome
2024

Pheochromocytoma-Induced Pseudo-Cushing’s Syndrome

Sample size: 1 publication Evidence: low

Author Information

Author(s): Małgorzata Bobrowicz, Anna Nagórska, Anna Karpiłowska, Marek Rosłon, Joanna Hubska, Adrianna Gładka, Sadegh Toutounchi, Łukasz Koperski, Urszula Ambroziak

Primary Institution: University Clinical Centre of the Medical University of Warsaw

Hypothesis

Can pheochromocytoma cause pseudo-Cushing’s syndrome?

Conclusion

The case highlights the successful resolution of pseudo-Cushing’s syndrome caused by pheochromocytoma through adrenalectomy and supportive care.

Supporting Evidence

  • The patient presented with pronounced weakness, loss of appetite, and poorly controlled hypertension.
  • Biochemical evaluation suggested ACTH-dependent hypercortisolemia.
  • Histopathological examination confirmed a pheochromocytoma.

Takeaway

A woman with a tumor in her adrenal gland had symptoms that looked like a different illness, but after surgery, she felt much better and her health improved.

Methodology

The patient underwent adrenalectomy after pre-treatment with doxazosin and metyrapone, along with supportive care.

Limitations

The case is based on a single patient, which may limit the generalizability of the findings.

Participant Demographics

A 66-year-old woman.

Digital Object Identifier (DOI)

10.3389/fendo.2024.1491873

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