HIV Prevalence and Impact on Renutrition in Children Hospitalised for Severe Malnutrition in Niger: An Argument for More Systematic Screening
2011

HIV Prevalence in Malnourished Children in Niger

Sample size: 477 publication Evidence: moderate

Author Information

Author(s): Madec Yoann, Germanaud David, Moya-Alvarez Violeta, Alkassoum Wafa, Issa Aichatou, Amadou Morou, Tchiombiano Stephanie, Pizzocolo Cecilia, Huber Florence, Diallo Sanata, Abdoulaye-Mamadou Roubanatou

Primary Institution: Unité d'Epidémiologie des maladies Emergentes, Institut Pasteur, Paris, France

Hypothesis

What is the prevalence of HIV among children hospitalized for severe malnutrition in Niger?

Conclusion

Around 9% of children hospitalized for severe malnutrition were HIV infected, highlighting the need for wider access to HIV testing in this population.

Supporting Evidence

  • HIV testing was accepted in 470 out of 477 children hospitalized for severe malnutrition.
  • The duration of renutrition was longer in HIV-positive children compared to HIV-negative children.
  • Mortality rates during renutrition were not significantly different between HIV-positive and HIV-negative children.

Takeaway

About 9 out of every 100 kids in the hospital for not getting enough food also have HIV, so we should check them for it more often.

Methodology

Retrospective study of children under 5 hospitalized for severe malnutrition, with HIV testing and analysis of renutrition duration and mortality.

Potential Biases

Potential selection bias due to the referral process and the high acceptance rate of HIV testing.

Limitations

The study is retrospective and based on medical records, which may introduce measurement errors.

Participant Demographics

Children under 5 years old, with a median age of 13 months; 55.3% boys and 44.7% girls.

Statistical Information

P-Value

0.003

Confidence Interval

95% CI: 6.2–11.5

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1371/journal.pone.0022787

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication