A rare cause of a common symptom, Anakinra is effective in the urticaria of Schnitzler Syndrome: a case report
2008
Anakinra is effective in treating Schnitzler Syndrome
Sample size: 1
publication
Evidence: low
Author Information
Author(s): Devlin Lisa A, Wright Gary, Edgar J David M
Primary Institution: Royal Hospitals, The Belfast Trust
Hypothesis
Can anakinra effectively treat urticaria in patients with Schnitzler Syndrome?
Conclusion
Anakinra is an effective treatment for Schnitzler Syndrome, which often mimics chronic idiopathic urticaria.
Supporting Evidence
- Anakinra led to a rapid and sustained clinical response in the patient.
- The patient had previously unresponsive chronic urticaria.
- Symptoms returned quickly upon stopping anakinra, indicating its effectiveness.
Takeaway
Schnitzler Syndrome can cause hives that don't go away with regular medicine, but a special drug called anakinra can help make the person feel better quickly.
Methodology
The case of a 43-year-old man with chronic urticaria unresponsive to conventional therapy was reported, and treatment with anakinra was initiated.
Limitations
Only one case is reported, limiting generalizability.
Participant Demographics
43-year-old Caucasian male.
Digital Object Identifier (DOI)
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