Ranitidine-induced thrombocytopenia: A rare drug reaction
2011

Ranitidine and Thrombocytopenia: A Case Study

Sample size: 1 publication 10 minutes Evidence: low

Author Information

Author(s): Amit V Bangia, Narendra Mohan, Vidushi

Primary Institution: Kasturba Medical College, Mangalore, India

Hypothesis

Can ranitidine cause thrombocytopenia in patients?

Conclusion

Ranitidine can induce thrombocytopenia, which improves after the drug is withdrawn.

Supporting Evidence

  • Only 29 cases of H2 receptor antagonist-induced thrombocytopenia have been reported.
  • The patient's blood counts improved significantly after stopping ranitidine.
  • Diagnosis of drug-induced thrombocytopenia is often based on clinical suspicion.

Takeaway

A woman got sick from a medicine called ranitidine, which made her blood platelets drop. When she stopped taking it, her blood got better.

Methodology

Case report of a 55-year-old female with thrombocytopenia after taking ranitidine.

Potential Biases

Potential bias in diagnosis due to reliance on clinical suspicion.

Limitations

Only one case is reported, limiting generalizability.

Participant Demographics

One 55-year-old female with pustular psoriasis.

Digital Object Identifier (DOI)

10.4103/0253-7613.75676

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