Blood Parameters in Pregnancy and Gestational Diabetes: A Review
Author Information
Author(s): Ghasemi Vida, Banaei Mojdeh, Kiani Zahra, Ramezani Tehrani Fahimeh, Saei Ghare Naz Marzieh
Primary Institution: Shahid Beheshti University of Medical Sciences
Hypothesis
What is the relationship between blood parameters and gestational diabetes mellitus (GDM) in pregnant women?
Conclusion
Women with GDM in the second trimester of pregnancy have higher levels of certain blood parameters compared to non-GDM pregnant women.
Supporting Evidence
- Women with GDM had significantly higher levels of haemoglobin, red blood cells, and white blood cells compared to controls.
- Lower levels of mean corpuscular haemoglobin concentration were found in women with GDM.
- Meta-analysis included 30 studies with a total of 13,720 individuals.
Takeaway
Pregnant women with gestational diabetes have different blood levels than those without it, which can help doctors understand and manage the condition better.
Methodology
Systematic review and meta-analysis of observational studies assessing blood parameters in relation to GDM.
Potential Biases
Potential publication bias and variability in study designs may affect the results.
Limitations
Heterogeneity among studies regarding diagnostic criteria for GDM and small sample sizes in some studies.
Participant Demographics
Participants included 3818 women with GDM and 9902 non-GDM women, with ages ranging from 26 to 30 years.
Statistical Information
P-Value
p=0.01
Confidence Interval
95% CI 0.134–0.553
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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