Psychosis After Mefloquine Use: A Case Report
Author Information
Author(s): Tran Tuan M, Browning Joseph, Dell Mary L
Primary Institution: Emory University School of Medicine
Hypothesis
Can therapeutic doses of mefloquine lead to neuropsychiatric symptoms such as psychosis?
Conclusion
Mefloquine can induce psychosis, which may be preceded by moderate symptoms like dizziness and anxiety.
Supporting Evidence
- Mefloquine is commonly used for malaria prophylaxis but can cause severe neuropsychiatric reactions.
- The patient experienced a range of symptoms including anxiety, paranoia, and psychosis after taking a high dose of mefloquine.
- Psychosis resolved with treatment using low-dose quetiapine.
Takeaway
Taking too much mefloquine can make you feel really anxious and confused, and sometimes it can even make you think things that aren't true.
Methodology
Case report detailing the symptoms and treatment of a patient who experienced psychosis after taking mefloquine.
Potential Biases
Potential bias due to reliance on self-reported symptoms and the subjective nature of psychiatric assessments.
Limitations
The case is based on a single patient, limiting generalizability.
Participant Demographics
37-year-old Nigerian male with a history of malaria and a single panic attack.
Digital Object Identifier (DOI)
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