Link Between Atypical Adenomatous Hyperplasia and Lung Cancer
Author Information
Author(s): Chapman A D, Kerr K M
Primary Institution: Department of Pathology, Aberdeen Royal Infirmary and Aberdeen University Medical School
Hypothesis
Is there an association between atypical adenomatous hyperplasia and primary lung cancer?
Conclusion
The study found a strong association between atypical adenomatous hyperplasia and primary lung adenocarcinoma.
Supporting Evidence
- AAH was found in 67 of 554 patients with primary lung carcinoma.
- AAH was more frequently found in adenocarcinoma (23.2%) than in other types of lung cancer.
- 30.2% of females with adenocarcinoma had AAH compared to 18.8% of males.
- Ten of the 67 patients with AAH had multiple primary cancers, all of which were adenocarcinoma.
Takeaway
The study looked at patients with lung cancer and found that some had a condition called atypical adenomatous hyperplasia, which might be linked to lung cancer.
Methodology
A systematic, prospective search for atypical adenomatous hyperplasia in lungs resected for cancer from 1989 to 1998.
Participant Demographics
The study included 554 patients, with a breakdown of 9.2% male and 19.0% female patients having atypical adenomatous hyperplasia.
Digital Object Identifier (DOI)
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