Fatal transfusion related acute lung injury following coronary artery by-pass surgery: a case report
2008

Fatal Transfusion Related Acute Lung Injury After Heart Surgery

Sample size: 1 publication Evidence: low

Author Information

Author(s): Bawany Fauzia Ahmad, Sharif Hasanat

Primary Institution: Aga Khan University

Hypothesis

What are the underlying mechanisms and risks associated with transfusion related acute lung injury (TRALI)?

Conclusion

The case highlights the need for awareness of TRALI as a potential complication following blood transfusions.

Supporting Evidence

  • TRALI is a potentially fatal complication of transfusion occurring in 1 per 5000.
  • This is the first documented case of TRALI from Pakistan.
  • The risk of TRALI increases if the donor is a multiparous female.
  • Patients with underlying cardiac conditions are at increased risk for TRALI.

Takeaway

Sometimes, when people get blood transfusions, they can have a serious reaction that makes it hard for them to breathe. This case shows that it can happen even after heart surgery.

Methodology

Case report detailing the clinical course of a patient who developed TRALI after receiving blood transfusions post-surgery.

Potential Biases

Potential bias in reporting due to the nature of a single case study.

Limitations

The case is based on a single patient, limiting generalizability.

Participant Demographics

68-year-old male, previously healthy, Asian origin, non-smoker.

Digital Object Identifier (DOI)

10.1186/1757-1626-1-372

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication