Effectiveness of Coartesiane® for Treating Malaria in Young Children
Author Information
Author(s): Chanda Pascalina, Hawela Moonga, Kango Mabvuto, Sipilanyambe Naawa
Primary Institution: National Malaria Control Centre
Hypothesis
Is Coartesiane® effective in treating uncomplicated malaria in children under five years old in Zambia?
Conclusion
Coartesiane® was effective in treating uncomplicated malaria in Zambian children weighing less than 10 kg.
Supporting Evidence
- 91 out of 111 children enrolled were successfully followed up.
- The Adequate Clinical and Parasitological Response (ACPR) was found to be 100%.
- Gametocyte levels significantly reduced from Day 0 to Day 7.
Takeaway
The study found that a special medicine called Coartesiane® works really well to help young kids with malaria feel better.
Methodology
The study was a one-arm, prospective evaluation of the clinical and parasitological response to treatment in children under five years old.
Limitations
The study was not a randomized clinical trial, which would have been ideal.
Participant Demographics
Children under five years of age, weighing less than 10 kg.
Statistical Information
Confidence Interval
95% CI 96.0;100
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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