Malignant Transformation of a Choroidal Nevus

Sample size: 1 publication Evidence: low

Author Information

Author(s): Muacevic Alexander, Adler John R, Li Luxi, Zhang Qiongyue, Zhang Peng

Primary Institution: Department of Ophthalmology, Xi'an No. 3 Hospital, the Affiliated Hospital of Northwest University, Xi'an, CHN

Can a choroidal nevus transform into malignant melanoma?

Choroidal nevus can transform into malignant melanoma, leading to severe complications and eventual death despite treatment.

Choroidal nevus is the most common intraocular tumor, with a low risk of transformation into melanoma.
The patient experienced blurred vision and was diagnosed with a choroidal nevus.
Bevacizumab treatment initially reduced subretinal fluid but did not prevent malignant transformation.
Transpupillary thermotherapy was performed due to the risk of malignant transformation.
The patient eventually died due to metastasis despite multiple treatment modalities.

A choroidal nevus is a common eye tumor that can sometimes turn into a dangerous cancer called melanoma, which can be very serious.

The case report involved multimodal fundus imaging and treatment with bevacizumab and transpupillary thermotherapy.

The study is based on a single case report, limiting generalizability.

A 45-year-old male patient.

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