Neurodevelopment of children exposed in utero to treatment of maternal malignancy
2001

Impact of Maternal Cancer Treatment on Child Development

publication

Author Information

Author(s): Nulman I, Laslo D, Fried S, Uleryk E, Lishner M, Koren G

Primary Institution: The Hospital for Sick Children, University of Toronto

Hypothesis

What are the long-term neurodevelopmental effects on children exposed in utero to maternal cancer treatment?

Conclusion

Maternal cancer treatment during pregnancy may negatively affect children's long-term neurodevelopment.

Supporting Evidence

  • Cancer complicates approximately 1 in 1000 pregnancies.
  • The occurrence of cancer during gestation is likely to increase due to delayed childbearing.
  • Most reports have focused on immediate morphologic observations at delivery.

Takeaway

If a mom has cancer while pregnant, the medicine she takes might affect how her baby grows and learns later on.

Limitations

Most studies have focused on immediate outcomes rather than long-term effects.

Digital Object Identifier (DOI)

10.1054/bjoc.2001.2090

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