Effect of Zinc on Prolactin Levels in Patients
Author Information
Author(s): Guiomar Madureira, Walter Bloise, Berenice Bilharinho Mendonca, Jos Brand.o-Neto
Primary Institution: Universidade de SAo Paulo
Hypothesis
Does zinc administration affect prolactin levels in hyperprolactinemic patients?
Conclusion
Zinc administration does not inhibit prolactin secretion in hyperprolactinemic patients.
Supporting Evidence
- Zinc levels increased significantly after acute and chronic administration.
- Prolactin levels did not change significantly after zinc administration.
- Patients had lower basal serum zinc levels compared to normal individuals.
Takeaway
The study looked at whether giving zinc to patients with high prolactin levels would help lower those levels, but it didn't work.
Methodology
The study involved measuring serum zinc and prolactin levels in patients before and after acute and chronic zinc administration.
Limitations
The small sample size and the specific patient population may limit the generalizability of the findings.
Participant Demographics
Seven females and one male, mean age 34 years.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
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