N-{4-[(2-Methoxyphenyl)sulfamoyl]phenyl}acetamide
2011
Study of a New Sulfonamide Compound
publication
Evidence: moderate
Author Information
Author(s): Ahmad Saba, Farrukh Muhammad Akhyar, Qureshi Fahim Ashraf, Adnan Ahmad, Akkurt Mehmet
Primary Institution: Government College University, Lahore, Pakistan
Hypothesis
The study investigates the structural properties of N-{4-[(2-methoxyphenyl)sulfamoyl]phenyl}acetamide.
Conclusion
The compound exhibits a distorted tetrahedral geometry and forms a three-dimensional network through hydrogen bonding.
Supporting Evidence
- The S atom in the compound has a distorted tetrahedral geometry.
- The two aromatic rings in the compound form a dihedral angle of 62.67°.
- An intramolecular hydrogen bond stabilizes the molecular conformation.
- The crystal structure features centrosymmetric dimers connected by hydrogen bonds.
Takeaway
The researchers looked at a new chemical compound and found that its structure is held together by special connections called hydrogen bonds.
Methodology
The compound was synthesized by reacting 2-methoxyaniline with 4-acetamidobenzenesulfonyl chloride in a controlled pH environment.
Digital Object Identifier (DOI)
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