Treatment of Cervical Chlamydial Infection With Amoxicillin/Clavulanate Potassium
1993

Effectiveness of Amoxicillin/Clavulanate in Treating Chlamydia

Sample size: 32 publication Evidence: high

Author Information

Author(s): Melinda S. Mann, Sebastian Faro, Maurizio L. Maccato, Raymond H. Kaufman

Primary Institution: Baylor College of Medicine

Hypothesis

Is amoxicillin/clavulanate potassium effective in the treatment of Chlamydia trachomatis endocervicitis?

Conclusion

Amoxicillin/clavulanate potassium is effective in eradicating C. trachomatis.

Supporting Evidence

  • All patients treated with amoxicillin/clavulanate potassium were cured of signs of cervicitis.
  • All patients were found to be free of C. trachomatis at their follow-up visits.
  • Augmentin was well tolerated, with minimal adverse effects.

Takeaway

The study found that a medicine called Augmentin can help get rid of a common infection called Chlamydia.

Methodology

Thirty-two patients with culture-proven endocervical infection were treated with amoxicillin/clavulanate potassium for 10 days, and follow-up cultures were taken at 2, 4, and 6 weeks.

Limitations

Some patients were excluded for not using condoms or for other reasons, which may affect the generalizability of the results.

Participant Demographics

The participants included 59% black, 29% Hispanic, and 12.5% Caucasian, with ages ranging from 14 to 66 years.

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