Tracking Drug-Resistant Streptococcus pneumoniae in Oregon
Author Information
Author(s): Arthur E. Chin, Katrina Hedberg, Paul R. Cieslak, Maureen Cassidy, Karen R. Stefonek, David W. Fleming
Primary Institution: Oregon Health Division
Hypothesis
Can aggregating existing hospital antibiograms provide community-specific antimicrobial susceptibility data for Streptococcus pneumoniae?
Conclusion
Antibiogram data can provide accurate, community-specific drug-resistant S. pneumoniae data in Oregon.
Supporting Evidence
- 86% of active surveillance isolates were susceptible to penicillin.
- 84% of aggregated isolates used by hospitals were susceptible to penicillin.
- Statistical comparisons showed no significant differences in susceptibility estimates between the two methods.
Takeaway
This study looked at whether hospitals' existing data on bacteria could help understand how many germs are resistant to antibiotics in the community.
Methodology
The study compared active surveillance data with aggregated antibiogram data from hospital laboratories.
Potential Biases
Antibiogram data may have been influenced by multiple isolates from a single patient.
Limitations
The active surveillance system had a case-isolate recovery rate of 67%, and antibiogram data may have included isolates from non-Portland-area residents.
Participant Demographics
Portland Tri-County area residents, population 1.2 million.
Statistical Information
Confidence Interval
95% CI = 80% to 91%
Statistical Significance
p>0.05
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