Overlap Between Functional Dyspepsia and Irritable Bowel Syndrome
Author Information
Author(s): WANG AnJiang, LIAO XianHua, XIONG LiShou, PENG Sui, XIAO YingLian, LIU SiChun, HU PinJin, CHEN MinHu
Primary Institution: Department of Gastroenterology, the First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, PR China
Hypothesis
What is the prevalence and risk factors for the overlap of functional dyspepsia and irritable bowel syndrome based on Rome III criteria?
Conclusion
Clinical overlap of functional dyspepsia and irritable bowel syndrome is very common, with the presence of postprandial fullness being a significant risk factor.
Supporting Evidence
- 5.0% of patients had FD-IBS overlap.
- 15.2% were classified as FD alone.
- 10.9% were classified as IBS alone.
- The odds ratio of having FD among IBS patients was 2.09.
- Patients with FD-IBS overlap had higher severity scores for postprandial fullness.
- Postprandial fullness was the only independent risk factor for FD-IBS overlap.
Takeaway
This study found that many people have both functional dyspepsia and irritable bowel syndrome, and feeling full after eating is a sign that might mean you have both.
Methodology
Patients completed a self-report questionnaire to determine the presence of functional dyspepsia and irritable bowel syndrome based on Rome III criteria.
Potential Biases
Potential bias due to self-reporting and the exclusion of patients with certain conditions.
Limitations
The study was conducted at a single hospital, and diagnoses were not confirmed by objective examinations.
Participant Demographics
The mean age of participants was 43.2 years, with 52.8% being female.
Statistical Information
P-Value
P < 0.001
Confidence Interval
95% CI: 1.68–2.59
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website