Seroprevalence of Measles Antibodies Among Migrant Populations: A Systematic Review and Meta-Analysis
2024

Measles Antibodies in Migrant Populations

Sample size: 42972 publication 10 minutes Evidence: high

Author Information

Author(s): Muacevic Alexander, Adler John R, Pradhan Somen K, Panda Ashutosh, Debata Ipsita, Panda Prem S

Primary Institution: Maharaja Krishna Chandra Gajapati Medical College & Hospital, Brahmapur, IND; Kalinga Institute of Medical Sciences, Bhubaneswar, IND

Hypothesis

What is the pooled seroprevalence of measles antibodies among migrant groups globally?

Conclusion

The overall pooled seroprevalence of measles antibodies among migrant communities is 83%, which is still below the threshold for herd immunity.

Supporting Evidence

  • The meta-analysis comprised 36 studies with a total of 42,972 participants.
  • Measles seroprevalence has been gradually increasing in more recent research.
  • Immunity levels are below the threshold needed for herd immunity, especially in children and refugees.
  • Significant heterogeneity was observed among the studies (I2 = 98%).
  • Catch-up vaccination programs are needed to close immunity gaps.

Takeaway

This study found that many migrants have low levels of measles antibodies, which means they are at risk for outbreaks. We need to help them get vaccinated.

Methodology

A systematic review and meta-analysis of observational studies documenting measles antibody seroprevalence among defined migrant groups.

Potential Biases

Potential publication bias may skew results, as studies with significant findings are more likely to be published.

Limitations

Regional variations in study methods and populations may limit the generalizability of findings.

Participant Demographics

The studies included various migrant groups, including refugees, asylum seekers, and internationally adopted children, with a mix of age groups.

Statistical Information

P-Value

p < 0.05

Confidence Interval

95% CI: 80%-87%

Statistical Significance

p < 0.01

Digital Object Identifier (DOI)

10.7759/cureus.74243

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