Recombinant Cytokines from Plants
2011
Recombinant Cytokines from Plants
publication
Evidence: moderate
Author Information
Author(s): Sirko Agnieszka, Vaněk Tomas, Góra-Sochacka Anna, Redkiewicz Patrycja
Primary Institution: Institute of Biochemistry and Biophysics Polish Academy of Sciences
Conclusion
Plant-based systems can be used to produce recombinant cytokines, but challenges remain in terms of yield and regulatory approval.
Supporting Evidence
- Plant-based platforms have been used for over 25 years to produce pharmaceutical proteins.
- Cytokines are important for treating various diseases but are expensive to produce.
- Several strategies have been developed to improve the yield of cytokines in plants.
Takeaway
Scientists are trying to make medicines from plants, which can help treat diseases, but it's hard to make enough of them and get permission to use them.
Methodology
The review summarizes various methods and strategies for producing recombinant cytokines in plant systems.
Limitations
The production yields of cytokines in plants are often low, and there are significant regulatory hurdles for commercialization.
Digital Object Identifier (DOI)
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