Chemotherapy for Advanced Thymomas
Author Information
Author(s): Berruti A, Borasio P, Gerbino A, Gorzegno G, Moschini T, Tampellini M, Ardissone F, Brizzi M P, Dolcetti A, Dogliotti L
Primary Institution: Università di Torino, Torino Italy
Hypothesis
The study aims to evaluate the impact of a specific chemotherapy regimen on patients with locally advanced thymomas.
Conclusion
The chemotherapy regimen is effective and manageable for treating locally advanced thymomas.
Supporting Evidence
- The overall response rate was 81.2%, with two complete responses and 11 partial responses.
- Nine patients were radically resected after chemotherapy.
- Median time to progression was 33.2 months and overall survival was 47.5 months.
Takeaway
Doctors gave special medicine to 16 patients with a type of tumor, and most of them got better or had their tumors removed.
Methodology
Patients received a chemotherapy regimen consisting of adriamycin, cisplatin, vincristine, and cyclophosphamide every three weeks.
Participant Demographics
Patients with stage III and IVa invasive thymoma.
Digital Object Identifier (DOI)
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