Human herpes virus-6 and leukaemias
Author Information
Author(s): Gentile G, Mele A, Ragona G, Faggioni A, Zompetta C, Tosti M E, Visani G, Castelli G, Pulsoni A, Monarca B, Martino P, Mandelli F
Primary Institution: G I M E M A (Gruppo Italiano Malattie Ematologiiche dell' Adulto)
Hypothesis
Is there an association between human herpes virus-6 seropositivity and different types of leukaemia?
Conclusion
The study found an association between increased HHV-6 seropositivity and acute myeloid leukaemia.
Supporting Evidence
- An association was shown between increased HHV-6 seropositivity and acute myeloid leukaemia.
- The adjusted odds ratio for the association was 1.20.
Takeaway
This study looked at whether a virus called HHV-6 is linked to certain types of blood cancer, and it found a connection with one type of leukaemia.
Methodology
A multicentre case-control study was conducted to investigate the relationship between HHV-6 antibody levels and various types of leukaemia.
Statistical Information
P-Value
0.022
Confidence Interval
1.07–1.33
Statistical Significance
p=0.022
Digital Object Identifier (DOI)
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