A pre-intervention study of malaria vector abundance in Rio Muni, Equatorial Guinea: Their role in malaria transmission and the incidence of insecticide resistance alleles
2008

Study of Malaria Vectors in Equatorial Guinea

Sample size: 6162 publication 10 minutes Evidence: moderate

Author Information

Author(s): Frances C Ridl, Chris Bass, Miguel Torrez, Dayanandan Govender, Varsha Ramdeen, Lee Yellot, Edu Amado Edjang, Christopher Schwabe, Peter Mohloai, Rajendra Maharaj, Immo Kleinschmidt

Primary Institution: Malaria Research Lead Programme, Medical Research Council

Hypothesis

What is the role of malaria vectors in transmission and the incidence of insecticide resistance alleles in Rio Muni, Equatorial Guinea?

Conclusion

Anopheles gambiae s.s. is the major malaria vector in Rio Muni, and high frequencies of insecticide resistance alleles were found before the control program began.

Supporting Evidence

  • A total of 6,162 Anopheles mosquitoes were collected.
  • Anopheles gambiae s.s. was identified as the major vector.
  • High frequencies of kdr alleles were found in the S-form of An. gambiae s.s.
  • No insensitive AChE was detected in the tested mosquitoes.
  • The study was conducted over eight months from December 2006 to July 2007.

Takeaway

This study looked at mosquitoes that spread malaria in Equatorial Guinea and found that one type of mosquito is the main culprit, while many have become resistant to insecticides.

Methodology

Mosquitoes were captured using window traps at 30 sites over eight months, identified to species, and tested for resistance alleles.

Limitations

The study only provides baseline data before the intervention and does not assess post-intervention effects.

Participant Demographics

The study focused on Anopheles mosquito populations in various provinces of Rio Muni.

Statistical Information

P-Value

p<0.001

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.1186/1475-2875-7-194

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