Early Outcomes of Mitral Valve Repair with Memo 4D Ring
Author Information
Author(s): Omer Dzemali, Hector Rodriguez Cetina Biefer, Marco Di Eusanio, Olivier Fabre, Giovanni Troise, Nikolaos Bonaros, Francesco Grimaldi, Yeong-Hoon Choi, Giuseppe Santarpino, Cristian Baeza, Francesco Pollari, Bertrand Marcheix, Davide Pacini, Vicenzo Argano, Max Baghai, Moninder Bhabra, Enzo Mazzaro, Luigi Badano, Joerg Kempfert
Primary Institution: University Hospital of Zurich, Zurich, Switzerland
Hypothesis
The Memo 4D annuloplasty ring will provide safe and effective outcomes for patients undergoing mitral valve repair.
Conclusion
Mitral valve repair with Memo 4D is associated with good clinical and haemodynamic outcomes in the early period.
Supporting Evidence
- 30-day mortality was 0.6%, with one stroke and one myocardial infarction reported.
- NYHA class improved significantly from preoperative to 30 days.
- KCCQ-12 summary score increased from 69.1 to 83.9 at 30 days.
- Mitral regurgitation significantly reduced after the operation.
- Left atrial volume decreased from 125.79 ml to 91.51 ml at 30 days.
- End-diastolic left ventricular diameter decreased from 55.19 mm to 52.70 mm at 30 days.
Takeaway
Doctors used a special ring to fix heart valves in 166 patients, and most of them felt better after the surgery.
Methodology
This was a prospective, multicentre study collecting clinical and echocardiographic outcomes preoperatively, at discharge, and at 30 days post-surgery.
Potential Biases
Potential biases due to the non-randomized design and lack of adjudication of patient inclusion.
Limitations
The study is observational, non-randomized, and lacks a comparative arm, with midterm and long-term data still pending.
Participant Demographics
Mean age 60.7 years, 31.3% female, with most patients having primary mitral valve disease.
Digital Object Identifier (DOI)
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