Ancient host–pathogen associations maintained by specificity of chemotaxis and antibiosis
2006

How Fungal Parasites Target Their Ant Hosts

Sample size: 100 publication 10 minutes Evidence: high

Author Information

Author(s): Gerardo Nicole M, Sarah R Jacobs, Cameron R Currie, Ulrich G Mueller

Primary Institution: University of Texas at Austin

Hypothesis

What specific mechanisms prevent parasitic fungi from infecting novel hosts?

Conclusion

The study shows that specific chemotactic and antibiotic responses help maintain host fidelity in the ancient association between fungus-growing ants and their fungal cultivars.

Supporting Evidence

  • Escovopsis fungi are attracted to their natural host cultivars more rapidly than to other fungi.
  • Cultivars can inhibit the growth of Escovopsis fungi that do not infect them in nature.
  • Genetic similarities between host and parasite strains influence infection outcomes.

Takeaway

Fungal parasites are really good at finding and infecting their favorite fungi, and they have special ways to avoid getting into trouble with other fungi that could stop them.

Methodology

The study used microbial bioassays to test how well Escovopsis fungi recognize and grow towards their host cultivars and how these cultivars defend against infection.

Limitations

The study was limited by the sample size for some bioassays, particularly with pink Escovopsis.

Statistical Information

P-Value

p = 0.03; p = 0.86; p = 0.88

Statistical Significance

p<0.01

Digital Object Identifier (DOI)

10.1371/journal.pbio.0040235

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