HPV Detection in Moroccan Nasopharyngeal Carcinoma Patients
Author Information
Author(s): Laantri Nadia, Attaleb Mohammed, Kandil Mostafa, Naji Fadwa, Mouttaki Tarik, Dardari R'kia, Belghmi Khalid, Benchakroun Nadia, El Mzibri Mohammed, Khyatti Meriem
Primary Institution: Institut Pasteur du Maroc
Hypothesis
NPC tumours from Moroccan patients harbour a specific HPV genotype.
Conclusion
EBV is commonly associated with NPC in Moroccan patients, and NPC tumours from these patients harbour high-risk HPV genotypes.
Supporting Evidence
- All NPC tumors were EBV positive.
- HPV DNA was found in 34% of NPC cases.
- HPV31 was the most common subtype found in the study.
Takeaway
This study looked at patients with a throat cancer called nasopharyngeal carcinoma and found that a virus called HPV is present in some of their tumors.
Methodology
Seventy Moroccan patients with NPC were screened for EBV and HPV using PCR amplification.
Limitations
The study's findings may not be generalizable due to the specific population and small sample size.
Participant Demographics
Mean age of patients was 39.65 years, with a male-to-female ratio of 2.33 to 1.
Digital Object Identifier (DOI)
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