The efficacy of intraoperative methylene blue enemas to assess the integrity of a colonic anastomosis
2007

Using Methylene Blue Enemas to Check Colonic Surgery Connections

Sample size: 229 publication Evidence: moderate

Author Information

Author(s): Smith Stanton, McGeehin William, Kozol Robert A, Giles David

Primary Institution: University of Connecticut School of Medicine

Hypothesis

The methylene blue enema (MBE) will prove as efficacious and efficient in identifying anastomotic leaks intraoperatively as other accepted methods of intraoperative testing.

Conclusion

The MBE can be applied to proximal and distal anastomosis, and patients with intraoperative leaks who underwent immediate repair did not develop clinical postoperative leaks.

Supporting Evidence

  • The intraoperative leak (IOL) rate was 4.5% for proximal anastomoses and 8% for distal anastomoses.
  • The postoperative leak (POL) rate was 3% of anastomosis.
  • There were no POLs in cases where an IOL led to concomitant intraoperative repair.
  • The MBE showed a specificity of 95% for predicting postoperative leaks.

Takeaway

Doctors used a special blue dye during colon surgery to check if the connections were leaking, and it worked well. If they found a leak and fixed it right away, the patients didn't have problems later.

Methodology

This study is a retrospective review of consecutive colonic operations performed from January 2001 to December 2004 in a community hospital setting by a general surgical group that uses the MBE exclusively.

Limitations

The small number of patients with postoperative leaks precludes statistical analysis of characteristics of patients with leaks compared to those without.

Participant Demographics

The mean age was 61 years, with 49% male, and operations were mostly elective (88.6%).

Digital Object Identifier (DOI)

10.1186/1471-2482-7-15

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