Metabolic syndrome and dietary components are associated with coronary artery disease risk score in free-living adults: a cross-sectional study
2011

Diet and Coronary Artery Disease Risk in Adults

Sample size: 362 publication 10 minutes Evidence: moderate

Author Information

Author(s): Takahashi Mauro Massao, de Oliveira Erick Prado, de Carvalho Ana Lygia Rochitti, de Souza Dantas Lidiane Affonso, Burini Franz Homero Paganini, Portero-McLellan Kátia Cristina, Burini Roberto Carlos

Primary Institution: Centre for Nutritional and Physical Exercise Metabolism, UNESP School of Medicine, Public Health Department, Botucatu City, São Paulo State, Brazil

Hypothesis

The study aims to evaluate the association of coronary artery disease risk score with dietary, anthropometric, and biochemical components in adults selected for a lifestyle modification program.

Conclusion

Recommended intake of saturated fat and dietary fiber, along with proper muscle mass, are inversely associated with coronary artery disease risk score.

Supporting Evidence

  • Individuals with metabolic syndrome had a higher CAD risk score.
  • Higher plasma uric acid levels were associated with increased CAD risk.
  • Recommended intake of saturated fat and dietary fiber acted as protective factors against CAD risk.

Takeaway

Eating less saturated fat and more fiber, while having good muscle mass, can help lower the risk of heart disease.

Methodology

A cross-sectional study involving 362 adults who underwent dietary recall, anthropometric measurements, and biochemical analyses to assess CAD risk.

Potential Biases

Potential bias due to reliance on self-reported dietary intake and the single-day recall method.

Limitations

The study's cross-sectional design limits causal inferences, and a single 24-hour dietary recall may not capture variability in food intake.

Participant Demographics

96 men and 266 women, average age 53.9 years, average BMI 28.5 kg/m2.

Statistical Information

P-Value

<0.0001

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1758-5996-3-7

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