Rotavirus G12 and Enteric Viruses in Diarrheal Children in Vietnam
Author Information
Author(s): Tra My Phan, Vu Rabaa, Maia A. Vinh, Ha Holmes, Edward C. Hoang, Nguyen Van Minh, Vinh Nguyen Thanh Phuong, Le Thi Tham, Nguyen Thi Bay, Phan Van Be Campbell, James I. Farrar, Jeremy Baker, Stephen Baker
Primary Institution: Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme, Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam
Hypothesis
What is the prevalence of major enteric viruses in hospitalized pediatric patients with diarrhea in urban and rural settings in southern Vietnam?
Conclusion
The study found a significant prevalence of rotavirus, particularly genotype G12, in children hospitalized with diarrhea in southern Vietnam, with notable differences between urban and rural areas.
Supporting Evidence
- Rotavirus was the most common pathogen identified in the study.
- Significant differences in rotavirus prevalence were observed between urban and rural locations.
- The study identified the emergence of rotavirus genotype G12 in Vietnam for the first time.
- Norovirus was also detected but at lower rates in the rural area compared to the urban area.
- Children under 24 months of age were the most affected demographic group.
Takeaway
Doctors looked at kids in Vietnam who had diarrhea to see what viruses were making them sick. They found that a lot of them had rotavirus, especially a new type called G12.
Methodology
The study screened fecal specimens from 362 hospitalized children for four viral gastrointestinal pathogens over a one-month period.
Potential Biases
Selection bias may have occurred due to the specific hospitals chosen for the study.
Limitations
The study was limited to a one-month snapshot and may not represent the full range of viral infections throughout the year.
Participant Demographics
Participants were children under 15 years old hospitalized with acute watery diarrhea.
Statistical Information
P-Value
0.0289
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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