Prevalence and Outcomes of Sepsis in Patients With Colon Carcinoma: Organism-Specific Analysis
2024

Sepsis in Colon Cancer Patients

Sample size: 876769 publication Evidence: high

Author Information

Author(s): Muacevic Alexander, Adler John R, Iqbal Rabia, Islam Zaigham ul, Bajwa Ahmad Taimoor, Mohammed Yaqub Nadeem, Kimball Henry, Samreen Syeda Daniya, Iqbal Qamar, Kasire Sripada Preetham, Ullah Asmat

Hypothesis

What is the prevalence and impact of sepsis on patients with colon carcinoma?

Conclusion

Sepsis significantly increases mortality, hospital stays, and healthcare costs in colon cancer patients.

Supporting Evidence

  • Patients with sepsis had significantly longer hospital stays and higher healthcare costs compared to those without sepsis.
  • The highest mortality rates were associated with Staphylococcus aureus, followed by Pseudomonas and MRSA.
  • Sepsis led to higher rates of complications, including acute kidney injury and septic shock.

Takeaway

This study shows that colon cancer patients who get sepsis have a much harder time and often stay in the hospital longer and pay more for their care.

Methodology

The study analyzed data from the National Inpatient Sample database, including patients aged over 18 with a primary diagnosis of colon cancer, comparing those with and without sepsis.

Potential Biases

Potential inaccuracies and missing data in the NIS database.

Limitations

The study is retrospective, may not represent the entire population, and lacks cancer-specific variables.

Participant Demographics

Mean age of patients was 67 years, with a mix of genders and races.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.7759/cureus.74175

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication