Effects of Boerhaavia diffusa on Cervical Cancer Cells
Author Information
Author(s): Rakhi Srivastava, Daman Saluja, Bilikere S. Dwarakanath, Madhu Chopra
Primary Institution: Dr. B. R. Ambedkar Center for Biomedical Research, University of Delhi
Hypothesis
The ethanolic extract of Boerhaavia diffusa has antiproliferative effects on cervical cancer cells.
Conclusion
The study found that the extract significantly inhibits the growth of HeLa cells, suggesting its potential as an anticancer agent.
Supporting Evidence
- The ethanolic extract of B. diffusa caused significant cell death in HeLa cells.
- BDF 5 treatment led to DNA fragmentation, a hallmark of apoptosis.
- Cell cycle analysis showed that BDF 5 inhibited DNA synthesis in HeLa cells.
Takeaway
This study shows that a plant called Boerhaavia diffusa can help stop cancer cells from growing.
Methodology
The study involved extracting compounds from Boerhaavia diffusa and testing their effects on HeLa cervical cancer cells using various assays.
Limitations
The study primarily focused on one type of cancer cell line and may not represent effects on other types.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website