Multimorbidity and health-related quality of life in the older population: results from the German KORA-Age study
2011

Impact of Multiple Chronic Conditions on Quality of Life in Older Adults

Sample size: 4565 publication 10 minutes Evidence: moderate

Author Information

Author(s): Matthias Hunger, Barbara Thorand, Michaela Schunk, Angela Döring, Petra Menn, Annette Peters, Rolf Holle

Primary Institution: Helmholtz Zentrum München, German Research Center for Environmental Health

Hypothesis

How do combinations of chronic conditions affect health-related quality of life in older adults?

Conclusion

The study found that interactions between coronary problems, diabetes, and stroke significantly impair health-related quality of life in older adults.

Supporting Evidence

  • The study found that stroke and chronic bronchitis had the greatest negative impact on health-related quality of life.
  • Patients with both diabetes and coronary disorders experienced more impairment than expected from their separate effects.
  • The study highlighted the importance of considering disease combinations rather than just individual conditions.

Takeaway

Having more than one chronic illness can make older people feel much worse than just having one. It's like having a cold and a headache at the same time; it feels worse than just one of them.

Methodology

The study used a population-based sample and a generalized additive regression model to analyze the effects of chronic conditions on health-related quality of life measured by the EQ-5D.

Potential Biases

Self-reported data may lead to underreporting or misclassification of chronic conditions.

Limitations

The study relied on self-reported chronic conditions and did not include psychiatric conditions or assess disease severity.

Participant Demographics

Participants were Germans aged 65 years or older, with a mean age of 73.9 years, and included 48.1% males.

Statistical Information

P-Value

<0.0001

Confidence Interval

95% confidence limits provided in the results

Statistical Significance

p<0.0001

Digital Object Identifier (DOI)

10.1186/1477-7525-9-53

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