Anaesthetic management in patients with glucose-6-phosphate dehydrogenase deficiency undergoing neurosurgical procedures
2011

Anaesthetic Management in G-6-PD Deficiency During Neurosurgery

Sample size: 2 publication Evidence: low

Author Information

Author(s): Valiaveedan Sebastian Mahajan, Charu Rath, Girija P Bindra, Ashish Marda, Manish K

Primary Institution: All India Institute of Medical Sciences, New Delhi, India

Conclusion

The anaesthetic management of patients with G-6-PD deficiency undergoing neurosurgery can be safely conducted by avoiding certain drugs and providing adequate analgesia.

Supporting Evidence

  • G-6-PD deficiency is an X-linked recessive condition that can lead to acute haemolysis.
  • The anaesthetic management should focus on avoiding drugs that can cause haemolysis.
  • Both patients underwent uneventful neurosurgical procedures with careful monitoring.

Takeaway

This study shows that children and adults with a specific enzyme deficiency can have surgery safely if doctors are careful about the medicines they use.

Methodology

Case reports of two patients with G-6-PD deficiency undergoing neurosurgical procedures were analyzed.

Limitations

The study is based on only two case reports, limiting the generalizability of the findings.

Participant Demographics

[{"age":2,"gender":"female","weight":13},{"age":36,"gender":"male","weight":61}]

Digital Object Identifier (DOI)

10.4103/0019-5049.76597

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