Host Factors and Fluconazole Resistant Candida Infections
Author Information
Author(s): Yang Yun-Liang, Cheng Ming-Fang, Chang Ya-Wen, Young Tzuu-Guang, Chi Hsin, Lee Sai Cheong, Cheung Bruno Man-Hon, Tseng Fan-Chen, Chen Tun-Chieh, Ho Yu-Huai, Shi Zhi-Yuan, Chan Chung-Huang Hubert, Lin Ju-Yu, Lo Hsiu-Jung
Primary Institution: National Chiao Tung University
Hypothesis
Do intrinsic host factors influence the colonization or infection by fluconazole resistant strains of Candida species?
Conclusion
The study found no significant difference in the frequency of colonization or infection by fluconazole resistant and susceptible Candida species based on host factors.
Supporting Evidence
- Fluconazole resistance was more frequent among isolates of Candida tropicalis compared to C. albicans and C. glabrata.
- Patients with pulmonary diseases and those receiving antituberculous agents showed higher rates of colonization or infection with resistant strains.
- The study included a total of 88 patients from nine hospitals.
Takeaway
This study looked at patients with yeast infections and found that whether the yeast was resistant to a drug called fluconazole didn't depend on the patients' health conditions.
Methodology
The study reviewed medical records of 88 patients from nine hospitals, comparing those with fluconazole resistant and susceptible Candida strains.
Potential Biases
Potential bias due to the selection of hospitals and patient records.
Limitations
The study was limited to patients from nine hospitals and may not represent all hospitalized patients.
Participant Demographics
Patients were hospitalized individuals with yeast infections, but specific demographics were not detailed.
Statistical Information
P-Value
0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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