Prevalence of insulin resistance and its association with metabolic syndrome criteria among Bolivian children and adolescents with obesity
2008

Insulin Resistance and Metabolic Syndrome in Bolivian Obese Children

Sample size: 61 publication Evidence: moderate

Author Information

Author(s): Caceres Margoth, Teran Carlos G, Rodriguez Susana, Medina Marcos

Primary Institution: Centro Pediatrico Albina PatiƱo, Cochabamba, Bolivia

Hypothesis

What is the association between insulin resistance and components of metabolic syndrome in Bolivian obese children and adolescents?

Conclusion

Metabolic syndrome has a prevalence of 36% in the studied population, with insulin resistance commonly associated with high blood pressure and high triglycerides.

Supporting Evidence

  • 36% of the children were diagnosed with metabolic syndrome.
  • 39.4% of the children exhibited insulin resistance.
  • Insulin resistance was significantly associated with high blood pressure and high triglycerides.

Takeaway

In Bolivia, many obese kids have a condition called metabolic syndrome, which can lead to serious health problems. This study found that a lot of these kids also have insulin resistance, which is linked to high blood pressure and high fat levels in their blood.

Methodology

The study involved 61 obese children and adolescents aged 5 to 18, who underwent glucose tolerance tests and blood tests to measure insulin and lipid levels.

Potential Biases

Potential bias due to socioeconomic factors affecting participation in the study.

Limitations

The sample size was small and may not represent the entire population of Bolivia.

Participant Demographics

Obese children and adolescents aged 5 to 18, with a near-equal distribution of males and females.

Statistical Information

P-Value

0.0148 for high blood pressure and 0.002 for high triglycerides correlation with insulin resistance.

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1471-2431-8-31

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