MOSAIC: A Database for Comparative Genomics of Bacterial Strains
Author Information
Author(s): Hélène Chiapello, Annie Gendrault, Christophe Caron, Jérome Blum, Marie-Agnès Petit, Meriem El Karoui
Primary Institution: INRA UR1077, Unité Mathématique, Informatique & Génome, Domaine de Vilvert, Jouy-en-Josas, France
Conclusion
The MOSAIC database now includes 493 pairwise comparisons and 35 multiple maximal comparisons representing 78 bacterial species.
Supporting Evidence
- The database provides easy access to comparisons of complete bacterial genomes.
- MOSAIC includes 493 pairwise and 35 multiple maximal comparisons.
- Genome conserved regions and variable segments are presented in various formats for analysis.
- The database allows for graphical visualization of aligned genomes.
Takeaway
MOSAIC is a tool that helps scientists compare the genomes of different bacteria to see how they are similar or different.
Methodology
The MOSAIC database uses algorithms like MGA and MAUVE to align bacterial genomes and categorize regions into conserved and variable segments.
Limitations
Some bacterial species with divergent genomes are not included in the database due to alignment challenges.
Digital Object Identifier (DOI)
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