Robotic Radiotherapy for Pelvic Recurrences
Author Information
Author(s): Dewas Sylvain, Bibault Jean Emmanuel, Mirabel Xavier, Nickers Philippe, Castelain Bernard, Lacornerie Thomas, Jarraya Hajer, Lartigau Eric
Primary Institution: Centre Oscar Lambret, Lille, France
Hypothesis
Can robotic image-guided radiotherapy be a viable alternative treatment for inoperable pelvic recurrences?
Conclusion
Robotic stereotactic radiotherapy can provide a short and well-tolerated treatment for lateral pelvic recurrences in previously irradiated areas.
Supporting Evidence
- The one-year local control rate was 51.4%.
- Median disease-free survival was 8.3 months after treatment.
- The overall median survival after treatment was 11.5 months.
- Acute toxicity was limited to grade 1 and 2 complications.
- Four of the eight patients with pain reported improvement in pain relief.
Takeaway
This study looked at using a special robot to give radiation treatment to patients with cancer that couldn't be operated on. It showed that this method can help some patients feel better.
Methodology
Sixteen patients with lateral pelvic lesions were treated with CyberKnife robotic radiotherapy, and their responses were evaluated using RECIST criteria.
Potential Biases
Potential selection bias due to the retrospective nature of the study.
Limitations
The study is limited by its small sample size and short follow-up period.
Participant Demographics
The cohort included 10 women and 6 men, with a mean age of 55 years.
Statistical Information
P-Value
0.09
Confidence Interval
95% IC: 49 to 77%
Statistical Significance
p = 0.09
Digital Object Identifier (DOI)
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