Pathways of Metastases from Primary Organs to the Ovaries
Author Information
Author(s): Yamanishi Yukio, Koshiyama Masafumi, Ohnaka Megumi, Ueda Masashi, Ukita Shingo, Hishikawa Kenji, Nagura Michikazu, Kim Tomoko, Hirose Masaya, Ozasa Hiroshi, Shirase Tomoyuki
Primary Institution: Otsu Red-Cross Hospital
Hypothesis
The rate of intravascular metastasis from the colorectum to the ovary is relatively higher than from the stomach to the ovary.
Conclusion
The study found that lymphatic metastasis from the stomach to the ovary is significantly higher than from the colon to the ovary.
Supporting Evidence
- 4 out of 7 gastric cancer cases showed ovarian lymphangio invasion.
- No ovarian vascular invasion was found in gastric cancer cases.
- 67% of colorectal cancer cases had ovarian vascular invasion.
- Patients with ovarian tumors treated simultaneously with original cancers had poorer prognosis.
Takeaway
This study looked at how cancer spreads to the ovaries from other organs and found that stomach cancer spreads there more often than colon cancer.
Methodology
The study reviewed 18 patients with metastatic ovarian tumors and examined microscopic and immunohistochemical findings.
Limitations
The study is limited by the small sample size and the retrospective nature of the analysis.
Participant Demographics
The average age of participants was 58 years, with origins of metastatic tumors from gastric and colorectal cancers.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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