Quality, topics, and demographic trends of animal systematic reviews - an umbrella review
2024

Quality and Trends of Animal Systematic Reviews

Sample size: 1358 publication 10 minutes Evidence: high

Author Information

Author(s): Hild Bernard Friedrich, Brüschweiler David, Hild Sophia Theodora Katharina, Bugajska Julia, von Wyl Viktor, Rosso Marianna, Wever Kimberley Elaine, Furrer Eva

Primary Institution: University of Zurich

Hypothesis

This study aimed to assess the quality and demographic trends of animal systematic reviews in neuroscience, including changes over time.

Conclusion

Animal systematic reviews in neuroscience are of overall high quality, but there are specific areas for enhancement such as the recommended pre-publication of study protocols.

Supporting Evidence

  • Animal systematic reviews are increasingly employed, covering a broad range of topics.
  • The most prolific countries in publishing systematic reviews are the USA, China, the UK, Brazil, and Iran.
  • The quality of systematic reviews is generally high and has improved over time.
  • Many common psychiatric diseases are underrepresented in systematic reviews.
  • Systematic reviews with a reported study protocol had higher quality scores compared to those without.

Takeaway

The study looked at many animal research reviews and found that while they are generally good, some topics need more attention and researchers should share their plans before starting.

Methodology

An umbrella review of animal systematic reviews was performed, searching Medline and Embase for reviews until January 27, 2023, using a validated data mining method for quality evaluation.

Potential Biases

Potential bias due to reliance on reported information and the lack of thorough examination of full texts for eligibility.

Limitations

The broad definition of systematic reviews may include some studies that do not strictly adhere to established definitions, and quality was assessed based on reported information which may not reflect actual execution quality.

Participant Demographics

The reviews originated from 64 countries, with notable contributions from the USA, China, UK, Brazil, and Iran.

Statistical Information

P-Value

p<0.001

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.1186/s12967-024-05992-0

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