A review on peripheral blood CD4+ T lymphocyte counts in healthy adult Indians
2010

CD4+ T Lymphocyte Counts in Healthy Adult Indians

Sample size: 1027 publication Evidence: moderate

Author Information

Author(s): Shete Ashwini, Thakar Madhuri, Abraham Philip, Raj Paranjape Ramesh

Primary Institution: National AIDS Research Institute (ICMR), Pune, India

Hypothesis

Establishing reference ranges for CD4+ T cell counts in the Indian population is necessary for understanding immune dysfunction.

Conclusion

The study highlights the need for standardized reference ranges for CD4+ T cell counts in healthy Indian adults to improve HIV disease management.

Supporting Evidence

  • CD4+ T cells are crucial for immune response and monitoring their counts is important for HIV management.
  • Existing reference ranges for CD4+ T cell counts in India are inadequate and vary significantly.
  • Standardized procedures and quality control are necessary for accurate CD4+ T cell count measurements.

Takeaway

This study is about counting special immune cells called CD4+ T cells in healthy adults in India, which helps doctors understand how well the immune system is working.

Methodology

The study reviewed and analyzed existing literature on CD4+ T cell counts in healthy Indian adults.

Potential Biases

Variations in sample collection, processing, and analysis methods could introduce bias.

Limitations

The data from various studies were generated using different methodologies and equipment, making it difficult to pool results.

Participant Demographics

Healthy adult Indians, with variations in studies across different geographic locations.

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