Linear response of mutans streptococci to increasing frequency of xylitol chewing gum use: a randomized controlled trial
2006

Effects of Chewing Xylitol Gum on Oral Bacteria

Sample size: 132 publication Evidence: moderate

Author Information

Author(s): Ly Kiet A, Milgrom Peter, Roberts Marilyn C, Yamaguchi David K, Rothen Marilynn, Mueller Greg

Primary Institution: University of Washington

Hypothesis

There is a linear reduction in mutans streptococci level in plaque and unstimulated saliva over five weeks in response to increasing frequency of xylitol chewing gum use at a constant daily dose of 10.32 g.

Conclusion

There was a linear reduction in mutans streptococci levels in plaque and saliva with increasing frequency of xylitol gum use at a constant daily dose.

Supporting Evidence

  • The study showed a linear reduction of mutans streptococci levels in plaque and saliva with increased frequency of xylitol gum use.
  • Participants who chewed xylitol gum more frequently had lower levels of harmful bacteria.
  • The results support the idea that higher frequency of xylitol consumption is necessary for effectiveness.

Takeaway

Chewing xylitol gum more often helps reduce bad bacteria in your mouth that cause cavities.

Methodology

Participants were randomized into groups to chew xylitol or placebo gum at different frequencies, and samples were taken to measure mutans streptococci levels.

Limitations

Plaque collection was not standardized by weight, which may affect quantitative analysis.

Participant Demographics

Mean age of participants was 34 years, with 57% women and a predominance of Caucasian participants.

Statistical Information

P-Value

p < 0.10

Statistical Significance

p < 0.10

Digital Object Identifier (DOI)

10.1186/1472-6831-6-6

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