Study of Tob1 Gene in Pig Muscle Development
Author Information
Author(s): Yuan Jing, Cao Ji-Yue, Tang Zhong-Lin, Wang Ning, Li Kui
Primary Institution: College of Veterinary Medicine, Huazhong Agricultural University
Hypothesis
The Tob1 gene plays a significant role in muscle development in pigs.
Conclusion
The Tob1 gene is differentially expressed during skeletal muscle development in pigs, suggesting its role in muscle growth and phenotypic differences between breeds.
Supporting Evidence
- The Tob1 gene was mapped to pig chromosome 12.
- Tob1 was highly expressed in skeletal muscle at 90 days post-conception in Tongcheng pigs.
- Tob1 expression patterns differed between Tongcheng and Landrace pigs during myogenesis.
- Tob1 expression increased with age in postnatal skeletal muscle.
- Tob1 was significantly increased at day 6 during C2C12 differentiation.
Takeaway
The Tob1 gene helps pigs grow muscles, and it works differently in different types of pigs.
Methodology
The study involved isolating and characterizing the Tob1 gene, analyzing its expression in different pig breeds at various developmental stages, and mapping its chromosome location.
Participant Demographics
The study involved Tongcheng and Landrace pig breeds.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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