Reply to: Questioning the role of HIPEC in patients with granulosa cell ovarian tumours
2024

Reply to Comments on HIPEC for Granulosa Cell Tumors

Sample size: 3 publication Evidence: low

Author Information

Author(s): Luis Felipe Falla-Zuniga, Armando Sardi, Mary Caitlin King, Vadim Gushchin

Primary Institution: Mercy Medical Center, Baltimore, MD, USA

Conclusion

CRS/HIPEC is a feasible therapeutic option for recurrent granulosa cell tumors, despite mixed survival outcomes.

Supporting Evidence

  • One patient remains disease-free 58.7 months after treatment.
  • Another patient had a recurrence but is currently disease-free after additional treatment.
  • One patient died due to complications without recurrence.

Takeaway

The study looked at three patients with a specific type of ovarian tumor who had surgery and a special treatment. One is doing well, one had a recurrence but is okay now, and one sadly passed away.

Methodology

The study involved three patients who underwent cytoreductive surgery and hyperthermic intraperitoneal chemotherapy.

Limitations

The small sample size limited the ability to perform Kaplan–Meier survival analysis.

Participant Demographics

All participants had granulosa cell tumors and underwent CRS/HIPEC.

Digital Object Identifier (DOI)

10.1515/pp-2024-0025

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