Insulin-like growth factors and cancer
1992

Insulin-like Growth Factors and Cancer

publication Evidence: moderate

Author Information

Author(s): V.M. Macaulay

Primary Institution: Institute of Cancer Research

Conclusion

Insulin-like growth factors (IGFs) play a significant role in tumor growth and may be important in cancer treatment strategies.

Supporting Evidence

  • IGFs are recognized as important mitogens in many tumor types.
  • IGF-I has been implicated in growth regulation of various neoplasia, especially common solid tumors.
  • IGF-II is associated with embryonal tumors and foetal development.

Takeaway

Insulin-like growth factors help tumors grow, and scientists are looking at ways to use this information to treat cancer.

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