Lions and Prions and Deer Demise
2008

Impact of Prion Disease on Mule Deer Survival

Sample size: 131 publication Evidence: high

Author Information

Author(s): Miller Michael W., Swanson Heather M., Wolfe Lisa L., Quartarone Fred G., Huwer Sherri L., Southwick Charles H., Lukacs Paul M.

Primary Institution: Colorado Division of Wildlife, Wildlife Research Center

Hypothesis

How does prion infection affect the survival of mule deer populations?

Conclusion

Prion infection significantly reduces the survival of mule deer and alters predator-prey dynamics.

Supporting Evidence

  • Prion infection lowered survival of adult mule deer from an estimated 5.2 years to only 1.6 years.
  • Nearly 75% of infected deer that died did so during winter months.
  • About one fourth of the adult deer sampled were infected with prion disease.
  • Prion infection increased the predation rate by mountain lions on deer.

Takeaway

When deer get sick from prion disease, they don't live as long, and more mountain lions start hunting them.

Methodology

A cohort study design was used to compare survival rates of prion-infected and uninfected mule deer.

Potential Biases

Potential bias in capturing and sampling deer may affect the results.

Limitations

The study was conducted in a specific area, which may limit the generalizability of the findings.

Participant Demographics

The study focused on free-ranging adult mule deer in Colorado, with a mix of male and female subjects.

Statistical Information

P-Value

0.0019

Confidence Interval

95% binomial CI 0.39–0.66 for infected deer; 95% binomial CI 0.70–0.91 for uninfected deer

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1371/journal.pone.0004019

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