Breast Cancer Genetic Risk Counseling in Scotland
Author Information
Author(s): Harry Campbell, S. Holloway, R. Cetnarskyj, E. Anderson, R. Rush, A. Fry, D. Gorman, M. Steel, M. Porteous
Primary Institution: University of Edinburgh Medical School
Hypothesis
Can a new model of cancer genetics service delivery improve referral rates for women with a family history of breast cancer?
Conclusion
The study found a significant increase in referral rates to cancer genetics services after implementing a new model of service delivery.
Supporting Evidence
- Referral rates increased by 48% during the trial.
- Women referred from community clinics had a higher increase in referral rates than those from regional clinics.
- Younger women were more likely to request referrals based on family history.
Takeaway
The study showed that more women are getting help for breast cancer risks when doctors are better connected to genetic services.
Methodology
A cluster randomised trial comparing referral rates before and during the trial across 203 general practices.
Potential Biases
Potential bias in referral rates based on GP characteristics and patient demographics.
Limitations
The study may not fully represent all regions due to its focus on South East Scotland.
Participant Demographics
Women with a family history of breast cancer referred by GPs.
Statistical Information
P-Value
<0.001
Confidence Interval
0.19–0.24 before trial; 0.28–0.34 during trial
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
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